Joost P H Drenth Selected Research

Alkaline Phosphatase

1/2019	Long-term efficacy and safety of obeticholic acid for patients with primary biliary cholangitis: 3-year results of an international open-label extension study.
8/2016	A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis.
4/2016	Alkaline phosphatase predicts response in polycystic liver disease during somatostatin analogue therapy: a pooled analysis.
2/2016	TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation.
2/2016	CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation.
12/2010	Relatively high risk for hepatocellular carcinoma in patients with primary biliary cirrhosis not responding to ursodeoxycholic acid.

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Joost P H Drenth Research Topics

Disease

50	Polycystic liver disease 12/2023 - 04/2004
38	Cysts 05/2023 - 04/2004
26	Autosomal Dominant Polycystic Kidney (ADPKD) 12/2023 - 12/2005
25	Fibrosis (Cirrhosis) 03/2024 - 02/2007
21	Infections 04/2022 - 10/2006
16	Autoimmune Hepatitis 03/2024 - 07/2010
14	Pancreatitis 03/2022 - 01/2005
14	Pain (Aches) 01/2022 - 10/2005
14	Chronic Pancreatitis 09/2015 - 07/2003
13	Abdominal Pain (Pain, Abdominal) 10/2023 - 06/2005
11	Gallstones (Gallstone) 10/2023 - 03/2013
10	Polycystic Kidney Diseases (Polycystic Kidney Disease) 01/2023 - 12/2005
10	Hepatitis C 12/2020 - 03/2010
10	Erythromelalgia (Erythermalgia) 10/2019 - 06/2005
10	Chronic Hepatitis C 01/2017 - 07/2008
8	Disease Progression 12/2023 - 07/2003
7	Liver Diseases (Liver Disease) 05/2024 - 10/2013
7	Hemorrhage 12/2023 - 12/2006
7	Non-alcoholic Fatty Liver Disease 01/2023 - 08/2014
7	Neoplasms (Cancer) 01/2021 - 10/2009
6	Inborn Genetic Diseases (Disease, Hereditary) 10/2022 - 06/2008
6	Inflammation (Inflammations) 10/2018 - 05/2004
6	Fever (Fevers) 12/2014 - 05/2004
5	Cholecystolithiasis 10/2023 - 03/2013
5	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2023 - 12/2010
5	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 06/2005
5	Crohn Disease (Crohn's Disease) 03/2013 - 07/2004
4	Hepatomegaly 05/2023 - 11/2014
4	Cholelithiasis 10/2021 - 12/2014
4	Channelopathies 01/2021 - 03/2008
4	Polyps 01/2021 - 01/2019
3	Adenoma (Adenomas) 02/2024 - 02/2006
3	Angiodysplasia 12/2023 - 11/2017
3	Hypertension (High Blood Pressure) 08/2023 - 12/2012
3	Pruritus (Itching) 01/2023 - 08/2016
3	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 12/2010
3	COVID-19 01/2022 - 01/2021
3	Hypercholesterolemia 01/2022 - 02/2016
3	Fatty Liver 01/2022 - 01/2019
3	Dyspnea (Shortness of Breath) 01/2020 - 03/2010
3	Adenocarcinoma 06/2013 - 10/2004
3	Mevalonate Kinase Deficiency 03/2013 - 05/2004
2	Liver Cirrhosis (Hepatic Cirrhosis) 05/2024 - 01/2019
2	Colic (Abdominal Cramps) 10/2023 - 01/2022
2	Kidney Diseases (Kidney Disease) 01/2023 - 01/2019

Drug/Important Bio-Agent (IBA)

29	1-dodecylpyridoxal (PLD)IBA 12/2023 - 12/2005
15	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 12/2023 - 11/2009
15	Proteins (Proteins, Gene)FDA Link 01/2023 - 04/2004
12	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2010
11	lanreotide (Somatuline)FDA Link 12/2023 - 11/2009
11	EnzymesIBA 11/2019 - 01/2004
10	Ribavirin (Virazole)FDA LinkGeneric 01/2017 - 07/2008
9	Azathioprine (Imuran)FDA LinkGeneric 03/2024 - 07/2010
8	Biomarkers (Surrogate Marker)IBA 09/2023 - 10/2009
8	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 03/2022 - 12/2006
7	Transaminases (Aminotransferases)IBA 08/2023 - 02/2016
7	DNA (Deoxyribonucleic Acid)IBA 12/2016 - 12/2006
7	Sodium Channels (Sodium Channel)IBA 11/2014 - 06/2005
6	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2023 - 12/2010
6	Alkaline PhosphataseIBA 01/2019 - 12/2010
5	Octreotide (Sandostatin)FDA LinkGeneric 12/2023 - 07/2013
5	Immunoglobulin G (IgG)IBA 08/2023 - 06/2020
5	Protein Kinase CIBA 01/2019 - 04/2004
5	Voltage-Gated Sodium ChannelsIBA 11/2014 - 06/2005
5	InterferonsIBA 01/2012 - 01/2009
4	Mycophenolic Acid (Cellcept)FDA LinkGeneric 03/2024 - 01/2022
4	Anti-Bacterial Agents (Antibiotics)IBA 04/2022 - 06/2009
4	SteroidsIBA 01/2020 - 01/2016
4	TrypsinogenIBA 09/2015 - 04/2008
3	Prednisolone (Predate)FDA LinkGeneric 03/2024 - 12/2022
3	AlbuminsIBA 08/2023 - 12/2010
3	LipidsIBA 01/2023 - 02/2020
3	Adenosine Triphosphatases (ATPase)IBA 01/2022 - 03/2018
3	AntibodiesIBA 01/2022 - 11/2008
3	Pain-FreeIBA 01/2022 - 10/2021
3	obeticholic acidIBA 01/2020 - 08/2016
3	Adrenal Cortex Hormones (Corticosteroids)IBA 11/2019 - 12/2012
3	Biosimilar PharmaceuticalsIBA 01/2019 - 11/2016
3	BilirubinIBA 01/2019 - 12/2010
3	Infliximab (Remicade)FDA Link 01/2019 - 03/2013
3	CT-P13IBA 01/2019 - 11/2016
3	SofosbuvirIBA 01/2017 - 01/2014
3	SodiumIBA 11/2014 - 03/2008
3	Amantadine (Aman)FDA LinkGeneric 06/2014 - 07/2010
3	Kazal Pancreatic Trypsin InhibitorIBA 08/2009 - 01/2007
3	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 08/2009 - 12/2005
3	LigandsIBA 06/2009 - 07/2004
3	Immunoglobulin D (IgD)IBA 03/2007 - 05/2004
2	Cytidine Triphosphate (CTP)IBA 03/2024 - 01/2018
2	Tacrolimus (Prograf)FDA LinkGeneric 01/2024 - 01/2022
2	Bile Acids and Salts (Bile Acids)IBA 12/2023 - 10/2015

Therapy/Procedure

39	Therapeutics 03/2024 - 09/2006
18	Cholecystectomy 10/2023 - 03/2013
7	Liver Transplantation 01/2023 - 02/2008
7	Sclerotherapy 06/2019 - 08/2008
4	Drug Therapy (Chemotherapy) 12/2020 - 10/2010
3	Laparoscopic Cholecystectomy 10/2023 - 01/2018
3	Stents 12/2021 - 10/2019
2	Remission Induction 03/2024 - 12/2023
2	Kidney Transplantation 01/2023 - 01/2017